The Rainbow Squirts are intended to represent a girls' organization like the real-life Girl Scouts or Brownies. The girls rollerskate around the neighborhood selling cookies.
Towards the end of "The Milkman Conspiracy", Razputin goes to the book depository and finds someone shooting at him and other G-Men on the way to the building. When Raz reaches the building, he finds out that the shooter is a Rainbow Squirt. The Rainbow Squirt jumps off the building and her box of cookies explodes and kills off some G-men. It is revealed that the cookies are actually explosives. Razputin eventually discovers the Squirts' meeting house and meets their leader, the Den Mother. Here, it is revealed the Rainbow Squirts harbor the secret hiding place of the Milkman, and they will do anything it takes to protect this secret.
They are killed in battle against Boyd Cooper's Censors and the G-Men, while Raz is battling the Den Mother. Pieces of their bodies can be seen lying on the ground outside their house. Raz can smash the bodies to reveal Arrowheads, health, and ammo.
- Using Clairvoyance on any Rainbow Squirt shows Raz as a grinning burglar stealing a milk bottle.
- If Raz picks up a Rainbow Squirt with Telekinesis, she'll threaten to scream for the police.
- One may notice that the Rainbow Squirts have no visible mouths.